Abstract: Taking Lanzhou City as the research object,this paper analyzed the land use changes in Lanzhou City from 2010 to 2020,and used the principal component analysis to study the main factors driving land use changes in Lanzhou City. The study drawn the following conclusions:(1)The cultivated land and forest land became grassland,urban-rural,and industrial and mining residential land,grassland became urban-rural,industrial and mining residential land,cultivated land,and other land became grassland in Lanzhou City between 2010 and 2020. (2)The comprehensive index of land use in Lanzhou City was constantly rising,and land use was in the development stage. Natural factors determined the land use change pattern in Lanzhou City in a certain extent.